Continuous lumbar cerebrospinal fluid drainage (CLCFD) is minimally invasive, controllable and easy to operate ( 4). Patients with cerebrospinal fluid leakage after craniocerebral injury are often treated with conventional lumbar puncture, but it is more traumatic. Therefore, timely and reasonable implementation of management measures is crucial to the prognosis of patients with cerebrospinal fluid leakage after craniocerebral injury surgery. This, coupled with other critical conditions, prolonged hospitalization, and more pipelines, can result in an increased risk of nosocomial infection ( 3). While this can be self-resolving within 1 week, there are many patients in whom this does not heal for a long time, and this can lead to intracranial infections and other complications, thus increasing the mortality rate. Conventional surgery is the most common clinical treatment for severe craniocerebral injury, but postoperative patients are prone to cerebrospinal fluid leakage. Severe craniocerebral injury is a common clinical condition with complexities and complications, and epidemiological reports suggest that the morbidity and mortality rate of severe craniocerebral injury as high as 45% ( 1, 2). CLCFD should be standardized in clinical operation to avoid infection.What is the implication, and what should change now? Systematic analysis on the cure rate and the incidence of intracranial infection showed that CLCFD can significantly improve the cure rate and reduce the incidence of intracranial infection compared with conventional lumbar puncture.Indicators such as cessation time of cerebrospinal fluid leakage, time to return to normal pressure, cerebrospinal fluid clearing time hospitalization time and complications, there have been more clinical studies reported.CLCFD is an effective and safe treatment compared to conventional lumbar puncture.The cessation time of cerebrospinal fluid leakage (95% confidence interval (CI): −3.65 to −2.86, Z=16.21, P0.05).Ĭonclusions: Compared with conventional lumbar puncture, CLCFD can significantly increase the cure rate, shorten the recovery time of cerebrospinal fluid, and significantly reduce the incidence of intracranial infections, reduce complications, is conducive to the prognosis of patients. There is some publication bias in the statistics. Results: A total of 8 studies, involving 568 patients.
#Cerebrospinal fluid leak in brain after head trauma software#
RevMan 5.3 software was used for systematic analysis. Cochrane systematic review was performed to assess the quality of the literature. Inclusion criteria: (I) randomized controlled trials (RCTs), CLCFD and conventional lumbar puncture drainage for patients with cerebrospinal fluid leakage after craniocerebral injury (II) evaluation of indicators such as cerebrospinal fluid leakage stop time, clearance time, intracranial infection and complications. Methods: The search terms ‘brain injury’ and ‘CLCFD’ were used to search CNKI, Wanfang, VIP, Longyuan, PubMed, Embase, Cochrane Library and other databases (from inception to November 1, 2022). This study evaluated the efficacy of CLCFD and conventional lumbar puncture in the treatment of cerebrospinal fluid leakage after craniocerebral injury. Therefore, there is no agreement on which method is more effective. However, CLCFD may also lead to complications such as intracranial hematoma and intracranial pneumothorax. CLCFD has less trauma, and drainage can be manipulated to avoid repeated lumbar puncture.
However, lumbar puncture is more invasive, requires multiple punctures.
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